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. 2022 Mar 5;127(4):449–457. doi: 10.1007/s11547-022-01465-w

Table 4.

Toxicity cohort (matched and unmatched cohorts)

Matched cohort
TOT (n = 185) SSRT (n = 90) SRT (n = 95) p-value
GI acute toxicity
Yes 45 (24.32%) 3 (3.33%) 42 (44.21%) < 0.001
No 140 (75.68%) 87 (96.67%) 53 (55.79%)
GU acute toxicity
Yes 54 (29.19%) 17 (18.89%) 37 (38.95%) 0.002
No 131 (70.81%) 73 (81.11%) 58 (61.05%)
GI late toxicity
Yes 11 (5.95%) 0 (0%) 11 (11.58%) 0.003
No 174 (94.05%) 90 (100%) 84 (88.42%)
GU late toxicity
Yes 22 (11.89%) 3 (3.33%) 19 (20%) < 0.001
No 163 (88.11%) 87 (96.67%) 76 (80%)
Unmatched cohort
TOT (n = 90) SSRT (n = 45) SRT (n = 45) p-value
GI acute toxicity
Yes 22 (24.44%) 2 (4.44%) 20 (44.44%) < 0.001
No 68 (75.56%) 43 (95.56%) 25 (55.56%)
GU acute toxicity
Yes 34 (37.78%) 13 (28.89%) 21 (46.67%) 0.08
No 56 (62.22%) 32 (71.11%) 24 (53.33%)
GI late toxicity
Yes 7 (7.78%) 0 (0%) 6 (13.33%) 0.04
No 83 (92.22%) 45 (100%) 39 (86.67%)
GU late toxicity
Yes 13 (14.44%) 3 (6.67%) 10 (22.22%) 0.03
No 77 (85.56%) 42 (93.33%) 35 (77.78%)

SSRT Stereotactic salvage radiation therapy, SRT Salvage radiation therapy, GI Gastro intestinal, GU Genitourinary