Table 2.
Blood eosinophil levels according to clinical, functional and CT characteristics
| Blood eosinophil counts | P value | ||
|---|---|---|---|
| Mean (SD) (95%CI) | n | ||
| Sex | |||
| Male | 194.8 (127.7) (181.1; 208.5) | 336 | < 0.0001 |
| Female | 158.1 (111.7) (147.0; 169.3) | 388 | |
| Age | |||
| 40–50 | 166.2 (123.4) (139.9; 192.5) | 87 | 0.848 |
| 50–60 | 178.5 (126.8) (161.1; 196.1) | 204 | |
| 60–70 | 173.0 (118.6) (157.3; 188.8) | 219 | |
| > 70 | 177.7 (116.4) (162.0; 193.4) | 214 | |
| BMI | |||
| Underweight | 166.8 (132.6) (44.2; 289.6) | 7 | 0.928 |
| Normal | 171.7 (136.8) (154.4; 189.0) | 243 | |
| Overweight | 178.3 (112.7) (165.6; 191.0) | 306 | |
| Obese | 173.9 (108.5) (157.2; 190.6) | 165 | |
| Smoking | |||
| Smoker | 189.4 (123.2) (172.2; 206.6) | 200 | 0.025 |
| Former smoker | 178.1 (123.3) (164.2; 192.1) | 303 | |
| Never smoker | 158.2 (113.1) (143.2; 173.2) | 221 | |
| Asthma diagnosis | |||
| Yes | 204.5 (142.0) (171.6; 237.4) | 74 | 0.027 |
| No | 171.8 (117.7) (162.8; 180.9) | 650 | |
| COPD | |||
| No | 160.7 (114.7) (149.4; 172.0) | 399 | 0.001 |
| GOLD I | 185.8 (115.9) (168.9; 202.8) | 183 | |
| GOLD II | 197.4 (133.4) (173.3; 221.5) | 120 | |
| GOLD III/IV | 227.0 (158.0) (157.0; 297.1) | 22 | |
| DLCO | |||
| > 80% | 170.8 (118.5) (160.8; 180.8) | 545 | 0.202 |
| < 80% | 184.2 (116.9) (166.2; 202.3) | 163 | |
| Exacerbations | |||
| 0 | 173.5 (119.2) (164.4; 182.5) | 667 | 0.222 |
| 1 or more | 195.0 (137.1) (158.6; 231.4) | 57 | |
| YPAS score | |||
| < 51 sedentary | 180.3 (122.1) (168.5; 192.0) | 416 | 0.207 |
| ≥ 51 non-sedentary | 169.2 (118.5) (155.6; 182.7) | 295 | |
| Emphysema | |||
| 0–10% | 173.0 (123.7) (161.9; 184.1) | 480 | 0.084 |
| > 10% | 190.3 (130.5) (167.9; 212.8) | 132 | |
| Airway Wall thickness (Primary Bronchi) | |||
| 0–20% | 179.9 (124.3) (168.9; 191.0) | 485 | 0.071 |
| > 20% | 164.4 (128.4) (141.9; 187.0) | 127 | |
| Airway Wall thickness (Secondary Bronchi) | |||
| 0–30% | 173.9 (119.5) (163.3; 184.5) | 489 | 0.192 |
| > 30% | 190.4 (146.0) (164.2; 216.7) | 121 | |
BMI body mass index, GOLD Global Initiative for Obstructive Lung Disease, COPD chronic obstructive pulmonary disease, YPAS Yale Physical Activity Questionnaire, DLCO diffusion capacity of the lung for carbon monoxide, CI confidence interval, SD standard deviation