FIGURE 2.

Forest plot showing RR of all‐cause 30‐day mortality. RR of all‐cause 30‐day mortality and 95% CI were calculated after PSM for the 2 treatment groups in the whole cohort and in the subgroups. Individual data were extracted from the ANNEXA‐4 study for the andexanet alfa–treated group and from the ORANGE study for the PCC‐treated group. Because of the low number of matches for the other major bleeds subgroup, the CI was large (RR, 1.29; 95% CI, 0.17‐9.55) and was not included in the forest plot. CI, confidence interval; GI, gastrointestinal; ICH, intracranial hemorrhage; PCC, prothrombin complex concentrate; PSM, propensity score matching; RR, relative risk