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. 2022 Mar 6;10:100218. doi: 10.1016/j.lana.2022.100218

Table 5.

Results of generalized additive models of standardized daily counts (per 100,000) of deaths from alcohol related liver failure by age group, race, sex, and urban/rural residence. Parameter estimates are given in differences in log counts.

Sex
A. parametric coefficients Estimate Std. Error t-value p sig.
(Intercept) -4.5343 0.0238 -190.9029 < 0.0001 ***
COVID-19 0.2613 0.2784 0.9384 0.348
Male 0.7762 0.0285 27.2179 < 0.0001 ***
COVID-19:Male 0.0984 0.0888 1.1079 0.2679
B. smooth terms edf Ref.df F-value p sig.
s(Date of death):Pre-COVID-19 2.6422 4.0000 8.3709 < 0.0001 ***
s(Date of death):COVID-19 0.0724 4.0000 0.0195 0.299
Age group
A. parametric coefficients Estimate Std. Error t-value p sig.
(Intercept) -3.7563 0.0218 -172.2304 < 0.0001 ***
COVID-19 0.0651 0.7656 0.0850 0.932
Age Over 65 -0.4108 0.0341 -12.0565 < 0.0001 ***
COVID-19:Age Over 65 0.2379 0.1005 2.3682 0.018 **
B. smooth terms edf Ref.df F-value p sig.
s(Date of death):Pre-COVID-19 2.9502 4.0000 13.2861 < 0.0001 ***
s(Date of death):COVID-19 0.3118 4.0000 0.1132 0.228
Black vs. white
A. parametric coefficients Estimate Std. Error t-value p sig.
(Intercept) -4.0009 0.1276 -31.3582 < 0.0001 ***
COVID-19 0.3610 0.3943 0.9156 0.360
Black (vs. white) -0.3971 0.2013 -1.9731 0.048 *
COVID-19:Black (vs. white) 0.0865 0.6147 0.1408 0.888
B. smooth terms edf Ref.df F-value p sig.
s(Date of death):Pre-COVID-19 0.0000 4.0000 0.0000 0.522
s(Date of death):COVID-19 0.0000 4.0000 0.0000 0.745
Urban vs. rural residence
A. parametric coefficients Estimate Std. Error t-value p sig.
(Intercept) -3.9056 0.0301 -129.7212 < 0.0001 ***
COVID-19 0.6166 0.0834 7.3940 < 0.0001 ***
Urban -0.2484 0.0447 -5.5598 < 0.0001 ***
COVID-19:Urban -0.2331 0.1311 -1.7780 0.075
B. smooth terms edf Ref.df F-value p sig.
s(Date of death):Pre-COVID-19 3.3870 4.0000 16.1938 < 0.0001 ***
s(Date of death):COVID-19 0.104001 4.0000 0.0000 0.628