TABLE 10.

Suppression of systemic immunologic reactivity: induction of mucosal tolerance with oral antigen feeding^a

Species	Disease	Antigen fed orally	Beneficial effectb
Human	Multiple sclerosis	Bovine myelin	±
Mouse or rat	EAE	MBP	+++
Human	Type I diabetes	Insulin	−
Mouse	Diabetes	Insulin	++
Human	Uveitis	Bovine S-antigen	+
Mouse	EAU	IRBP	++
Human	Rheumatoid arthritis	Chicken type III cartilage	+
Mouse	Collagen-induced arthritis	Type II collagen peptides	+++
Mouse	Colitis	Haptenized colonic protein	++
Mouse	Thyroiditis	Thyroglobulin	++
Rat	Transplantation	Alloantigens-MHC peptides	++

^aData taken from reference 90. 

^b−, not known; ±, some; +++, highly significant.