Multivariate adjusted hazard ratios and 95% confidence intervals of cardiovascular diseases were estimated from Cox proportional hazards models, adjusted for sex, age, race, assessment center, Townsend deprivation index, income, family history of CVDs, medical history of cancer, diabetes, hypertension, angina, symptom of depression/anxiety, high cholesterol, insulin treatment, antihypertensive drugs, lipid treatment, aspirin use, hypnotics/antidepressants/anti-anxiety drugs, and body mass index. CI, confidence interval; CVD, cardiovascular disease; HR, hazard ratio; MI, myocardial infarction.