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. 2022 Mar 5;8:99. doi: 10.1038/s41420-022-00902-z

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Fig. 3 — A NSUN5 knockdown and overexpression in BMSCs confirmed by western blotting. *p < 0.05. B Compared with control cells, GPX4 expression was downregulated by NSUN5 depletion in BMSCs treated with erastin. *p < 0.05. C, D Total iron concentrations (C) and Fe²⁺ levels (D) were enhanced by NSUN5 knockdown. *p < 0.05. E–H Erastin-induced ROS production (E, F) and lipid peroxidation (G, H) were increased by NSUN5 depletion and reduced by NSUN5 overexpression, *p < 0.05 (C–H).