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. 2022 Feb 7;18(4):1651–1662. doi: 10.7150/ijbs.63297

Figure 6.

Figure 6

Keap-NRF2 signaling contributes to the Notch1 protected mitochondrial bioenergetics and NADPH oxidase activity in H/R injured adult cardiomyocyte. (A) The mitochondrial bioenergetics was measured by the Seahorse XFp Extracellular Flux Analyzer; (B) The maximal respiration (MR) and spare respiratory capacity (SPR) were analyzed; (C) The protein level of total Keap1, total NRF2 and neclues NRF2 were analyzed by Western Blot; (D) The activity of NADPH oxidase was analyzed by ELISA kit; *P<0.05, **P<0.01 verses indicated group. N=3.