Table 2.
Univariate and multivariate analysis of different parameters for Overall Survival in CRC patients
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95%CI) | p value | HR (95%CI) | p value | |
| Gender (male vs female) | 1.170 (0.691-1.980) | 0.559 | ||
| Age ( >67 vs ≤67) | 1.721 (1.017-2.913) | 0.043* | ||
| Clinical stage (III-IV vs I-II) | 8.542 (4.785-15.248) | <0.001*** | 7.690 (4.248-13.921) | <0.001*** |
| Histological grade (G3 vs G1-G2) | 7.586 (3.407-16.888) | <0.001*** | 2.719 (1.205-6.138) | 0.016* |
| Recurrence (YES vs NO) | 2.411 (0.962-6.041) | 0.06 | ||
| TSG-6 expression (High vs Low) | 1.970 (1.174-3.307) | 0.010* | ||
Univariate and multivariate Cox proportional hazards regression were used to calculate Hazard ratio (HR), 95% confidence intervals (95% CI) and p values in SPSS 24.0. TSG-6 Low is defined as IHC score≤4 and TSG-6 High is defined as IHC score >4. *p<0.05, **p<0.01, ***p<0.001.