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. 2022 Jan 16;18(4):1347–1362. doi: 10.7150/ijbs.67974

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LncRNA-COX2 interacts with EGR1. (A) qRT-PCR analysis of the expression of EGR1 in fibroblasts treated with TGF-β or not and (B) epidural tissues from surgical site and normal region of mice. (C) qRT-PCR analysis of EGR1 level in fibroblasts after LncRNA-COX2 overexpression. (D) Western blot analysis of EGR1 in fibroblasts in treated with TGF-β or after LncRNA-COX2 overexpression. (E) Predicted binding sites of LncRNA-COX2 and EGR1. Mut-1, mutated site 1; Mut-2, mutated site 2; Mut-3, mutated both sites 1 and 2. *P<0.05, **P<0.01.