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. 2022 Feb;11(1):25–28. doi: 10.5582/irdr.2022.01011

Figure 1.

Figure 1.

Dot plot distributions of missense Z-scores, GeVIR, number of CCRs in 99th percentile for highly constrained genes (those with a probability of loss-of-function intolerance of 1) for different Mendelian modes of inheritance. Figure prepared with https://huygens.science.uva.nl/PlotsOfData/.