Table 2.

Unconditional Mixed-Effects Growth Models of Study Outcomes

	Pain Severity			Pain Interference			Depressive Symptoms			Anxiety Symptoms			Opioid Misuse Behaviors
Predictors	B	95% CI	p	B	95% CI	p	B	95% CI	p	B	95% CI	p	B	95% CI	p
Intercept	4.18	4.09 – 4.27	< .001	4.90	4.77 – 5.02	< .001	58.05	57.52 – 58.57	< .001	59.34	58.85 – 59.83	< .001	43.63	42.97 – 43.30	< .001
Linear Time	−.15	−.19 – −.11	< .001	−.11	−.17 – −.06	< .001	−.37	−.57 – −.17	< .001	−.12	−.17 – −.08	< .001	−.03	−.10 – .03	.310
Curvature Time	.01	.01 – .01	< .001	.01	.00 – .01	.003	.02	.01 – .04	.008	—	—	—	—	—	—