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. 2022 Feb 21;12:818868. doi: 10.3389/fonc.2022.818868

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Copyright © 2022 Xie, Zhang, Li, Zhang, Li, Zheng and Lai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction of the LRG prognostic signature in TCGA cohort. (A) Identification of the prognosis-related differentially expressed LRGs by univariate Cox regression analysis. (B, C) LASSO Cox regression analysis of 16 prognosis-related differentially expressed LRGs. (D) Forest plot of the six target genes that compose the LRG signature. (E) The expression levels of six target genes by qRT-PCR. (F) The Kaplan Meier analysis of the six target genes *P < 0.05; **P < 0.01;***P < 0.001.