Figure 6.

Inferred abundances of 40 different cell types in gastric tissues

(A and B) Biopsy cohort and (B) surgery cohort. Cell-type enrichment analysis was performed using a gene signature-based approach (xCell). The xCell score serves as a proxy for the abundance of the corresponding cell type. In the biopsy cohort, B cell infiltration was more abundant in the HP-associated gastritis group than in the gastric cancer group. Enriched B cell infiltration in the severe gastritis tissues was also observed in the surgery cohort. The x axis indicates each sample in the biopsy and surgery cohorts. The prefix of each sample label denotes the study group (A_: healthy stomach, B_: post-HP eradication, C_: HP-associated gastritis, D_: gastric cancer [biopsy cohort], GC_: gastric cancer [surgery cohort], and SG_: severe gastritis). The y axis indicates the xCell score. HP, Helicobacter pylori; SG, severe gastritis; GC, gastric cancer.