Figure 6.

CPT2 deficiency does not induce myosin heavy chain isoform switching. (A) Representative images and (B) quantification of control and Cpt2^Sk−/− muscles by immunofluorescent detection of myosin heavy chain isoforms: MyHC-β (Type I, blue), MyHC-2B (Type IIb, red), MyHC-2A (Type IIa, green), or no stain (Type IIx, black). Myofiber perimeter is demonstrated with dystrophin (yellow or pink). EDL, extensor digitorum longus. Data are presented as mean ± SEM. N = 3. Magnification 20X. Scale bar = 200 μm.