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. 2001 Jul;14(3):561–583. doi: 10.1128/CMR.14.3.561-583.2001

TABLE 1.

Age and sex of patients and laboratory method used to confirm the diagnosis in cases of Whipple's disease published since 1991a

Age (yr) Sexb Result by:
Publication yr (reference)
PAS staining PCR amplification Electron microscopy
47 F + 1991 (6)
64 (mean) 12M, 2F + 1991 (11)
35 M + + 1991 (14)
59 F + 1991 (42)
37 M + + 1991 (92)
53 F + + 1991 (141)
70 F + + 1991 (207)
32 M + + 1991 (210)
51 (mean) 13M, 3F + + 1992 (55)
36 M + 1992 (145)
36 M + + + 1992 (154)
51 M + +
50 M + +
52 M + +
48 M + + +
36 M + + 1992 (163)
62 M + 1992 (187)
71 M + 1993 (35)
45 M + 1993 (73)
58 M + + + 1993 (134)
64 F + 1993 (162)
39 M +
45 M + 1993 (180)
43 M +
28 M + 1993 (212)
65 F + + 1994 (13)
59 M + + 1994 (33)
62d F + + 1994 (82)
59 M + +
47e M + 1994 (106)
61 (mean) 24M, 3F + 1994 (120)
65 M + 1995 (40)
59 F + + + 1995 (155)
6 M + 1995 (183)
43 M + + 1995 (201)
31 F + + 1996 (5)
63 M + + 1996 (12)
35 M + 1996 (21)
55 M + 1996 (26)
60 M + 1996 (31)
49 M + 1996 (38)
4 M + 1996 (49)
58 F + + 1996 (67)
44 M + + 1996 (61)
46 M + + 1996 (68)
31 M + 1996 (96)
55 M + + 1996 (105)
47f F
54f M
50 M + + 1996 (168)
63 M + 1996 (194)
55 (mean) 38M, 14F + 1997 (50)
40 M + + + 1997 (54)
55 M + 1997 (94)
47 F + 1997 (107)
60f M
63f M
55f M
48f W
59 M + + + 1997 (108)
50 M + 1997 (116)
61 M + + 1997 (117)
51 F + 1997 (119)
46g M
58g M
60 M + + 1997 (124)
22 M + + 1997 (129)
8 F +
38 M + +
72 F + +
62 F + +
48 M + + + 1997 (131)
42 F + + 1997 (133)
65 M + +
53 M + 1997 (142)
70 M + 1997 (144)
58 F + +
35 F + + 1997 (149)
54 (mean) 13M, 4F + + 1997 (150)
58 M + 1997 (165)
44 F + + 1997 (174)
65 M + + 1997 (193)
52 (mean) 94M, 16F + (+)c 1997 (199)
62 F + + 1998 (30)
63 (mean) 12M + 1998 (43)
44 M + + 1998 (98)
59 M + 1998 (101)
32 M + + 1998 (130)
34 M + + 1998 (136)
58 M + + + 1998 (143)
55 M + + 1998 (166)
66 M + + 1998 (167)
77 F + + + 1998 (185)
62 M + + + 1998 (204)
54 F + 1999 (8)
36 M + + 1999 (22)
40 M + + 1999 (27)
55 M + +
75 M + 1999 (39)
43 M + + 1999 (57)
47 F + + 1999 (78)
64 M + + 1999 (79)
53 M + +
55 M +
55 F + +
48 M + 1999 (83)
72 M +
50 M +
32 F +
30 F +
59 M +
47 M + 1999 (115)
36 M + + 1999 (127)
41 M + 1999 (138)
61 M + +
62 M + + 1999 (148)
75 M + +
50 M + +
65 M + +
64 M + +
29 F + +
48 M + +
a

Patients redundantly described in more than one reference are reported only once (based on the information provided by the authors in the different manuscripts). Laboratory results refer to intestinal or extraintestinal specimens. Spaces in the table indicate “not determined.” 

b

M, male; F, female. 

c

For 39 patients histology was also confirmed by PCR. 

d

Patient with Whipple's disease-associated bacterial organism infection. 

e

Gram-positive rods detected. 

f

Clinically diagnosed. 

g

No data about PAS, PCR, and electron microscopy.