Table 4.

Summary of Biomechanical Tensile Testing Experiments for Rat Left Ventricular Myocardium After Infarction. Studies reporting rat left ventricle (LV) tensile modulus are summarized, including type of tensile testing and type of therapy after myocardial infarction (MI), if any. Our current work represents the first study of rat LV biomechanics after MI in postnatal day 1 (P1) neonatal rats. C, circumferential; L, longitudinal. ~ denotes data values estimated from the source manuscript.

Reference	Tissue/Therapy	Method	Modulus
Current Work	P1 neonatal rat LV 6 weeks after MI (with natural regeneration) Adult rat LV 4 weeks after MI No therapy	Biaxial tensile testing	Neonate Sham: C: 274 kPa L: 277 kPa Neonate MI (with natural regeneration): C: 268 kPa L: 269 kPa Adult Sham: C: 180 kPa L: 172 kPa Adult MI: C: 322 kPa L: 315 kPa
Wang et al., 2019	Adult rat LV 4 weeks after MI ± angiogenic cytokine therapy	Biaxial tensile testing	Sham: C: 220 kPa L: 209 kPa MI: C: 264 kPa L: 258 kPa MI + therapy: C: 212 kPa L: 195 kPa
Sirry et al., 2018	Adult rat LV 4 weeks after MI No therapy	Biaxial tensile testing	MI: C: 1218 kPa L: 487 kPa
Shudo et al., 2015	Adult rat LV 4 weeks after MI ± cell sheet therapy	Uniaxial tensile testing	Sham: ~140 kPa MI: ~400 kPa MI + therapy: ~250 kPa
Atluri et al., 2013	Adult rat LV 6 weeks after MI ± cell scaffold therapy	Uniaxial tensile testing	Sham: 193 kPa MI: 304 kPa MI + therapy: 239 kPa
MacArthur et al., 2013	Adult rat LV 4 weeks after MI ± angiogenic cytokine therapy	Uniaxial tensile testing	Sham: 195 kPa MI: 301 kPa MI + therapy: 252 kPa