FIGURE. 1.

Sensitivity of BC to 5‐Fu is negatively correlated with the level of CCAT2. Note: A, expression of CCAT2 in normal breast tissues (n = 90) and BC tissues before (n = 100) and after neoadjuvant chemotherapy (n = 70) (PR +SD + PD); B, Kendall's tau‐b correlation analysis was used to detect the correlation between the effect of neoadjuvant chemotherapy and CCAT2 expression; C, expression of CCAT2 in BC cells and their corresponding drug‐resistant cells. The measurement data were expressed as mean ±standard deviation in panels A and C. For comparisons between two groups, independent t‐test was used for comparisons when compared to normal tissues group or MCF10A group. * p < 0.05; paired t‐test was used for comparisons when compared to tumour tissues pre‐neoadjuvant chemotherapy or corresponding BC non‐drug‐resistant cell lines, # p < 0.05. For comparisons among multi‐groups, one‐way ANOVA was used for comparisons. Tukey's multiple comparisons test was used for the post hoc test