FIGURE. 5.

CCAT2 mediates the occurrence of BC and its sensitivity to 5‐Fu. Note: (A), changes of tumour volume in nude mice in each group; (B), the level of CCAT2 in transplanted tumour tissues in nude mice in each group; (C), immunohistochemistry was conducted to detect the Ki‐67 in xenografts of nude mice in each group (× 400) and positive expression rate of Ki‐67; (D), Western blot analysis was applied to detect expression of mTOR pathway‐related factors in transplanted tumour tissue; (E), Western blot analysis was used to test apoptosis‐related factors in transplanted tumour tissue. The measurement data were expressed as mean ±standard deviation. Paired t‐test was used for comparisons between two groups and one‐way ANOVA was used for comparisons. Tukey's multiple comparisons test was used for the post hoc test. Compared with the NC group, * p < 0.05, compared with the CCAT2 group, # p < 0.05