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. 2022 Feb 21;13:839489. doi: 10.3389/fimmu.2022.839489

Figure 5.

Figure 5

Antibody secretions of total IgG (A), isotypes IgG1 (B), and IgG2 (C) in the sera from immunized animals at weeks 0, 2, and 4. Each serum was conducted once, and significance was evaluated by one-way ANOVA followed by Dunnett’s test. Values among the TgP2-pVAX1, TgP2-pVAX1/PLGA, and TgP2-pVAX1/CS groups were pairwise compared by ANOVA following Bonferroni’s correction. Values are shown as the mean of the OD450 ± SD (n = 5). *p < 0.05, **p < 0.01, and ***p < 0.001 compared with blank or control group.