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. 2022 Feb 21;13:839489. doi: 10.3389/fimmu.2022.839489

Table 1.

Immunization strategy in mice.

Group Immunization strategy (each mouse) Challenge strategy (each mouse)
Blank Equal volume of PBS at weeks 0 and 2 103 tachyzoites were challenged intraperitoneally at week 4
Control 100 μg of pVAX1 plasmid at weeks 0 and 2
pVAX1/CS pVAX1/CS nanospheres containing 100 μg of pVAX1 plasmid at weeks 0 and 2
pVAX1/PLGA pVAX1/PLGA nanospheres containing 100 μg of pVAX1 plasmid at weeks 0 and 2
TgP2-pVAX1 100 μg of TgP2-pVAX1 plasmid at weeks 0 and 2
TgP2-pVAX1/CS TgP2-pVAX1/CS nanospheres containing 100 μg of TgP2-pVAX1 plasmid at weeks 0 and 2
TgP2-pVAX1/PLGA TgP2-pVAX1/PLGA nanospheres containing 100 μg of TgP2-pVAX1 plasmid at weeks 0 and 2