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MAPKs signaling pathway in the LDLR−/− mice. Protein was extracted from mice aorta (A) and liver tissue (C). Then the total and phosphorylated levels of JNK, ERK1/2, p38 and NF-κB P65 were determined by western blotting assay, n = 3. (B,D) The quantitative results were depicted. CON means control group, MOD means model group, AS-IV means Astragaloside IV group, ATO means Atorvastatin group. Data are expressed as mean ± SD. **p < 0.01 versus CON group; ##p < 0.01 versus MOD group.
