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. 2022 Feb 21;13:828269. doi: 10.3389/fphar.2022.828269

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Copyright © 2022 Sachetto, Miyamoto, Tashima, de Souza and Santoro.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activity of rutin, RS and SA on the fluorescence spectra of (A) BjV and (B) jararhagin. Data were expressed as RFU. Activity of rutin, RS, SA, AEBSF (SVSP inhibitor) and o-phe (SVMP inhibitor) on enzymatic activities of BjV protein families in vitro: (C) LAAO, (D) hyaluronidase, (E) SVSP and (F) SVMP. SA and o-phe were tested only for SVMP activity, and AEBSF was tested only for SVSP activity. Data were expressed as percentage of the maximum enzymatic activity; assays were carried out in duplicates/triplicates.