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. 2022 Mar 7;8(1):00786-2020. doi: 10.1183/23120541.00786-2020

TABLE 4.

Incident rates of arrhythmia, myocardial infarction, hip fracture, opportunistic infection and sensorineural hearing loss among new users of inhaled corticosteroids and macrolide monotherapy with bronchiectasis

Outcome Inhaled corticosteroid Macrolide monotherapy
Events Patient-years Incidence rate # Events Patient-years Incidence rate #
Arrhythmia 9508 31 395 30.3 (29.7–30.9) 728 2855 25.5 (23.7–27.4)
Myocardial infarction 892 34 688 2.6 (2.4–2.8) 81 3171 2.6 (2.0–3.2)
Hip fracture 919 34 661 2.7 (2.5–2.8) 77 3173 2.4 (1.9–3.0)
Opportunistic infection 1585 34 200 4.6 (4.4–4.9) 180 3113 5.8 (5.0–6.7)
Sensorineural hearing loss 2574 33 491 7.7 (7.4–8.0) 347 2993 11.6 (10.4–12.9)

#: incidence rate per 100 patient-years (95% confidence interval).