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. 2022 Feb 21;9:752833. doi: 10.3389/fnut.2022.752833

Table 3.

Effects of tea drinking on cognitive function and cognition-related brain regions.

Characteristics Tea drinkers
(n = 54)
Non-tea drinkers
n = 57)
T P
Age, y 69.67 ± 7.697 71.28 ± 8.079 −1.076 0.284
Education, y 9.08 ± 4.300 8.61 ± 4.218 0.564 0.574
Male, n (%) 35 (64.8) 37 (64.9) 1.000 0.574
Smoker, n (%) 23 (42.6) 16 (28.1) 2.566 0.117
Drinker, n (%) 15 (27.8) 8 (14.0) 3.188 0.101
Take exercise, n (%) 32 (59.3) 34 (59.6) 0.002 1.000
Hobby, n (%) 37 (68.5) 29 (50.9) 3.580 0.082
Hypertension, n (%) 20 (37.0) 21 (36.8) 0 1.000
Diabetes, n (%) 7 (13.0) 6 (10.5) 0.159 0.733
Brain structure
Total brain volume, cm3 1485.44 ± 131.605 1475.91 ± 135.964 0.375 0.709
Center hippocampus, mm3 3676.10 ± 384.162 3574.24 ± 472.829 1.242 0.217
Right hippocampus, mm3 3852.21 ± 451.510 3783.28 ± 499.481 0.761 0.448
CC_anterior, mm3 854.76 ± 146.967 879.43 ± 145.036 −0.890 0.375
CC_Central, mm3 451.85 ± 102.669 466.18 ± 100.002 −0.745 0.458
CC_posterior, mm3 950.42 ± 181.166 1023.41 ± 172.956 −2.172 0.032*
Neuropsychological tests
Baseline MoCA 24.66 ± 3.937 23.86 ± 4.228 1.026 0.307
Follow-up of MoCA 23.61 ± 4.451 23.22 ± 5.357 0.317 0.752
MoCA change value 0.008 ± 0.155 −0.049 ± 0.236 1.148 0.256
Baseline ALT 6.92 ± 3.142 5.68 ± 3.216 2.044 0.043*
Follow-up of ALT 6.80 ± 3.008 6.13 ± 4.647 0.700 0.486
ALT change value −0.198 ± 0.738 −0.404 ± 1.023 0.932 0.355
*

p < 0.05; CC means corpus callosum; ALT, Associative learning test.