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. 2022 Feb 21;10:818905. doi: 10.3389/fbioe.2022.818905

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Copyright © 2022 Ding, Ling, Shi and Zheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Heat map of the top 20 upregulated and downregulated lncRNAs. The upregulated and downregulated genes are marked red and blue, respectively. The top 10 mRNAs related to differentially expressed lncRNAs were selected as target genes. The Kyoto Encyclopedia of Genes (B) and Genomes and Gene Ontology (C) analysis maps of the target genes were drawn.