Table 1.
Cohort characteristics for the 5789 MESA participants included in the analysis
| Variable | |
|---|---|
| Age, years | 62.6 (10.2) |
| Male sex | 2777 (48.0) |
| Ethnicity | |
| White | 2156 (37.2) |
| Chinese | 705 (12.2) |
| Black | 1666 (28.8) |
| Hispanic | 1262 (21.8) |
| Diabetes | 742 (12.8) |
| Hypertension | 2635 (45.5) |
| Anti-hypertensive medication | 2186 (37.8) |
| Total cholesterol, mg/dL | 194.0 (35.8) |
| HDL cholesterol, mg/dL | 50.9 (14.9) |
| Systolic BP, mmHg | 127.0 (21.5) |
| Diastolic BP, mmHg | 72.0 (10.3) |
| Smoking history | |
| Never | 2903 (50.1) |
| Former | 2139 (36.9) |
| Current | 727 (12.6) |
| BMI, kg/m2 | 28.3 (5.5) |
| Family history of MI | 2313 (40.0) |
| hs-CRP, mg/L | 1.90 [0.84, 4.20] |
| Calibrated factor VIII | 94 [73, 120] |
| Fibrinogen antigen, mg/dL | 338 [295, 389] |
| Plasmin–antiplasmin complex, nM | 4.44 [3.45, 5.70] |
| D-dimer, μg/mL | 0.23 [0.13, 0.37] |
| PLG, mg/dL | 11.8 [8.1, 15.3] |
| OxPL-PLG, nM | 82.6 [60.5, 110.8] |
| Lp(a), mg/dL | 17.8 [7.75, 41.0] |
| Atherosclerotic cardiovascular disease eventsa | 877 (15.1) |
| Myocardial Infarction | 282 (4.9) |
| Definite/probable angina | 306 (5.3) |
| Resuscitated cardiac arrest | 34 (0.6) |
| Stroke (not TIA) | 275 (4.8) |
| Death from ASCVD | 211 (3.6) |
Data are shown as mean (standard deviation), n (%), or median [Q1, Q3].
ASCVD, atherosclerotic cardiovascular disease; BMI, body mass index; HDL, high-density lipoprotein; BP, blood pressure; hs-CRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein; Lp(a), lipoprotein(a); MI, myocardial infarction; TIA, transient ischemic attack; OxPL, oxidized phospholipids; PLG, plasminogen; Q1, first quartile (25th percentile); Q3, third quartile (75th percentile).
a
Total represents first events.