Figure 5.

FCP-Tph/HA improves the antiproliferative effects of FCP and Tph in vivo. A). Schematic of tumor formation and injection of drugs to the tumor. B) Tumor growth profiles after treatment with different formulations. C) Plot of body weight versus time in tumor-bearing mice. (n = 5). (n.s.) p > 0.05, (*) p < 0.05, (***) p < 0.001 compared with normal saline (Control). D) Images of tumors after the final treatment. Scale bar, 1 cm. E) Histological analysis of tumor section stained with H&E, TUNEL, and Ki67 for mice with different treatment groups. Nuclei were stained with DAPI (blue), TUNEL (green), and Ki67 (red). Scale bars, 40 μm.