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Proposed model for the negative regulation of Parkin-mitophagy by FoxP3 responsible for cardiac remodeling and the effect of triptolide. ATF4, activating transcription factor 4; Atg, autophagy-related protein; FoxP3, Forkhead/winged helix-transcription factor P3; LC3, microtubule-associated protein 1 light chain 3; PE, phosphatidyl ethanolamine; Ub, ubiquitin.
