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. 2022 Feb 7;12(5):2115–2132. doi: 10.7150/thno.69424

Figure 6.

Figure 6

(A) Chemical structure of copolymers poly(methacrylic acid)-graft-poly(ethyleneglycol methacrylate) (p(MAA-g-EGMA)). (B) Schematic structure of the studied magnetic drug delivery systems. Evolution with time of (C) Tumor volume and (E)% weight change of mice (n=4) after i.v. injections with: saline (Control), nanocarriers without the drug (Blank), aqueous cisplatin solution (FD), cisplatin-loaded nanocarriers (PD), and cisplatin-loaded nanocarriers in the presence of an external magnetic field in the tumor area (PDMF). Arrows in (a) and (b) represent tail vein injection events. (D) Pictures of the tumors taken at the end of the study period are shown for comparison. (F) Spleen index of mice sacrificed at the end of the in vivo experiment. Adapted with permission from ref 99, copyright 2016 Elsevier.