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Timeline of major milestones in three generations of first-line Pt drug clinical application
| Generation | Pt Drug | Molecular Structure | Market Time | Listed Country |
|---|---|---|---|---|
| First | Cisplatin |
|
1978 | Japan/Italy |
| Second | Carboplatin |
|
1986 | America |
| Third | Oxaliplatin |
|
1996 | France |
