Skip to main content
. 2022 Feb 14;12(5):2205–2231. doi: 10.7150/thno.70756

Figure 4.

Figure 4

PBM treatment attenuates amyloid load and abnormal Tau hyperphosphorylation. (A) Representative immunofluorescence staining for Aβ (4G8) in both the cortex and hippocampus (a). The numbers of plaques (b), Aβ plaque load (c), and the cumulative frequency distribution of the size of the plaque (d) in both the cortex and hippocampus were analyzed. Scale bar = 400 µm. n = 5. (B) Representative 3D reconstruction of amyloid plaques (a) and the analysis of amyloid plaques volume (b). (C) Detergent-soluble and detergent-insoluble Aβ (1-40) and Aβ (1-42) were measured in both the cortex and hippocampus. (E) Representative immunofluorescence staining for PHF1. Scale bar = 20 µm. Data are presented as mean ± SEM (n = 6). *P < 0.05 versus WT group, # P < 0.05 versus AD group.