Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 21;12(5):2266–2289. doi: 10.7150/thno.66663

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

Dynamic changes in cellular FPN with intracellular bacteria. (A) Confocal images of FPN co-localized with BL21 over time in macrophages. DAPI-stained cell nucleus. Green fluorescence is BL21. Ferroportin antibody-stained FPN. Scale bar = 5 µm. (B) Co-localization of FPN with bacteria by immunoelectron microscopy and colloidal gold labeling. Scale bar = 200 nm (C) Knockdown efficiency of FPN by immunoblotting. (D-E) Bactericidal efficiency of macrophages after FPN knockdown. (F) Intracellular bactericidal effects of hepcidin pre-treatment. (G) Intracellular bactericidal effects of hepcidin post-treatment. n = 3, ns = not significant, **p < 0.01, ***p < 0.001, ****p < 0.0001.