Table 1.
Variable/group | LT (trough <3 µg/mL) |
MT (trough 3–6 µg/mL) |
HT (trough >6 µg/mL) |
P value |
(n=7) | (n=16) | (n=10) | ||
Male (n, (%)) | 4 (57.1) | 11 (68.7) | 5 (50.0) | 0.646 |
Age (years) | 68.6±6.0 | 73.7±7.0 | 74.6±9.4 | 0.168 |
IBW (kg) | 61.8±17.2 | 58.3±7.8 | 57.6±8.0 | 0.944 |
APACHE II score | 14.4±6.1 | 16.5±3.3 | 16.6±4.9 | 0.619 |
SOFA score | 5.6±2.6 | 5.7±1.1 | 4.5±1.9 | 0.244 |
CrCL | 74.5±24.6 | 57.5±13.8 | 57.8±14.5 | 0.226 |
uNGAL | 11.1±9.3 | 23.4±23.8 | 31.3±37.2 | 0.209 |
APACHE, acute physiology and chronic health evaluation; CrCL, creatinine clearance; HT, high trough; IBW, ideal body weight; LT, low trough; MT, moderate trough; SOFA, sequential organ failure assessment; uNGAL, urine neutrophil gelatinase-associated lipocalin.