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. 2021 Jul 20;29(e1):e63–e66. doi: 10.1136/ejhpharm-2021-002868

Table 1.

Baseline demographics and clinical parameters of the patients

Variable/group LT
(trough <3 µg/mL)
MT
(trough 3–6 µg/mL)
HT
(trough >6 µg/mL)
P value
(n=7) (n=16) (n=10)
Male (n, (%)) 4 (57.1) 11 (68.7) 5 (50.0) 0.646
Age (years) 68.6±6.0 73.7±7.0 74.6±9.4 0.168
IBW (kg) 61.8±17.2 58.3±7.8 57.6±8.0 0.944
APACHE II score 14.4±6.1 16.5±3.3 16.6±4.9 0.619
SOFA score 5.6±2.6 5.7±1.1 4.5±1.9 0.244
CrCL 74.5±24.6 57.5±13.8 57.8±14.5 0.226
uNGAL 11.1±9.3 23.4±23.8 31.3±37.2 0.209

APACHE, acute physiology and chronic health evaluation; CrCL, creatinine clearance; HT, high trough; IBW, ideal body weight; LT, low trough; MT, moderate trough; SOFA, sequential organ failure assessment; uNGAL, urine neutrophil gelatinase-associated lipocalin.