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. 2022 Feb 21;13:752189. doi: 10.3389/fimmu.2022.752189

Figure 1.

Figure 1

Increased RNASE2 mRNA expression in PBMCs from SLE patients. (A) Detection of RNASE2 expression by real-time PCR in PBMCs from 37 healthy controls (HC), 60 SLE patients, 20 patients with rheumatoid arthritis (RA) and 20 patients with primary Sjögren’s syndrome (SS). (B–E) Associations of RNASE2 mRNA levels with SLE disease activity index (SLEDAI) score, the amount of 24hour proteinuria as well as the levels of serum creatinine and uric acid by the Pearson or Spearman correlation test. (F–I) RNASE2 mRNA expression in SLE patients with or without positive anti-SSA, anti-Sm, anti-dsDNA or anti-SSB antibodies. Data are presented as mean ± SEM, *p < 0.05, **p < 0.01, ****p < 0.0001.