Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 21;13:752189. doi: 10.3389/fimmu.2022.752189

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Zhu, Tang, Xu, Wu, Liu, Geng, Ma, Tsao, Feng and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Association of age-associated B cells subset (ABCs) with RNASE2 expression in SLE patients. (A) PBMCs from 24 HC, 26 SLE, 5 RA and 6 SS patients was collected and analyzed for the proportion of CD11c⁺T-bet⁺ cells in CD19⁺ B cells by flow cytometry. (B, C) The percentage of CD11c⁺T-bet⁺ B cells was related to SLE disease activity score (SLEDAI and BILAG) (by Spearman correlation test). (D) The percentage of CD11c⁺T-bet⁺ B cells was associated with the amount of 24hour proteinuria (by Spearman correlation test). (E) The proportion of CD11c⁺T-bet⁺ B cells was increased in SLE patients with positive anti-Sm antibody. (F) The proportion of CD11c⁺T-bet⁺ B cells was closely related to RNASE2 mRNA levels in SLE patients (n=14). Data are presented as mean ± SEM, *p < 0.05.