Figure 4.

Microglial STAT3 deletion alleviated the neuronal loss after SAH. (A) Neuronal loss was detected by NeuN immunohistochemistry in the CAPS, M1 cortex and hippocampus of the brain. The representative NeuN labelled coronal brain sections were shown on day 5 after SAH. (B) NeuN-positive neurons were quantified in the aforementioned brain areas of STAT3 KO and control groups of mice. Bar=50 µm. STAT3 KO n=7, control n=8. Values are ean±SEM. *P≤0.05, **P≤0.01, ***P≤0.001. CAPS, cortex adjacent to the perforated site; KO, knockout; SAH, subarachnoid haemorrhage; STAT3, signal transducer and activator of transcription 3.