Table 4.

Age stratification analysis

Age stratification	No. of studies	OR and 95% CI of GI symptom for mortality	P value of OR	No. of studies that average age: GI group >non GI group	No. of studies that average age: GI group <non-GI group
0–39	3	2.36 [0.88; 6.33]	0.088	NA	NA
40–49	8	2.22 [0.96; 5.11]	0.061	5 (83.3%)	1 (16.7%)
50–59	15	1.09 [0.85; 1.40]	0.517	3 (33.3%)	6 (66.7%)
60–69	18	0.71 [0.54; 0.95]	0.02	0 (0%)	6 (100%)
70~	7	0.40 [0.21; 0.76]	0.006	0	1 (100%)

OR, odds ratio; CI, confidence interval; GI, gastrointestinal; NA, data are not available because the studies in the subgroups did not report the age information of patients with/without GI symptoms