Table 4. Results from risk analyses (univariate and multivariate logistic regression, ORs, 95% CI in parentheses IDHmut-non-codel n=85).
| MR features | Univariate logistic regression | Multivariate logistic regression |
|---|---|---|
| Necrosis | ||
| Negative | Reference | |
| Positive | 1.059 (0.303–3.706) | |
| Hemorrhage | ||
| Negative | Reference | |
| Positive | 0.702 (0.074–6.645) | |
| Degree of enhancement | ||
| Negative | Reference | |
| Positive | 1.806 (0.638–5.117) | |
| Proportion CE tumor | ||
| Negative | Reference | |
| Positive | 1.402 (0.495–3.968) | |
| Enhancing margin | ||
| Well-defined | Reference | |
| Poorly-defined | 0.941 (0.225–3.939) | |
| Extranodular growth | ||
| Negative | Reference | |
| Positive | 4.297 (1.031–17.916)* | 4.297 (1.031–17.916)* |
| T1 + C/T2 mismatch | ||
| Negative | Reference | |
| Positive | 2.292 (0.468–11.224) | |
| CS | ||
| >30 mm | Reference | |
| ≤30 mm | 0.994 (0.362–2.725) | |
| Location | ||
| Other | Reference | |
| Frontal lobe | 0.447 (0.146–1.367) | |
| SVZ | ||
| Negative | Reference | |
| Positive | 4.167 (1.115–15.568)* | |
| Volume | ||
| <60 cm3 | Reference | |
| ≥60 cm3 | 3.404 (0.715–16.206) | |
| Intratumoral vascular | ||
| Negative | Reference | |
| Positive | 0.702 (0.060–8.164) | |
| Length | ||
| < median | Reference | |
| ≥ median | 2.900 (0.952–8.83) | |
| Width | ||
| < median | Reference | |
| ≥ median | 1.641 (0.564–4.771) | |
| Depth | ||
| < median | Reference | |
| ≥ median | 2.275 (0.787–6.572) | |
| Length-width ratio | ||
| < median | Reference | |
| ≥ median | 2.679 (0.960–7.47) | |
| Length-depth ratio | ||
| < median | Reference | |
| ≥ median | 1.313 (0.491–3.510) | |
| Width-depth ratio | ||
| < median | Reference | |
| ≥ median | 1.239 (0.468–3.28) | |
| Volume | ||
| < median | Reference | |
| ≥ median | 2.55 (0.836–7.776) | |
*, P<0.05. ORs, odds ratios; IDHmut-non-codel, lower-grade glioma with IDH mutation and no 1p/19q codeletion; MR, magnetic resonance; CE, contrast-enhanced; CS, the shortest distance between the edge of the lateral and the tumor centroid; SVZ, subventricular zone.