Figure 3.
Gene expression of markers of inflammation in subcutaneous abdominal adipose tissue. Expression of genes encoding for cytokines [PAI-1 (encoded by SERPINE1), TNF-α, IL-1β, IL-6, CCL2, CCL3, CCL5, CXCL16, IL-10] and for proteins highly expressed in macrophages (CD68 and CD206, encoded by MRC1) and lipid-associated macrophages (TREM2) in SAAT in LEAN, OB-NL and OB-NAFLD groups. Values are means ± SEM *Value significantly different from the LEAN value, P < .05. †Value significantly different from the OB-NL value, P < .05. #linear trend, P < .05.