Table 1.

Proportion of Articles in This Review in Which Certain Mediation Assumptions Were Addressed

Study Characteristic	% of Articles (n = 206)
Temporal ordering of exposure and mediator	43.7
Temporal ordering of mediator and outcome	30.6
Temporal ordering of exposure, mediator, and outcome	23.8
Adjusted for covariates	60.7
Adjusted for covariates that include baseline measure of mediator	13.6
Adjusted for covariates that include baseline measure of outcome	16.0
Adjusted for covariates that include baseline measures of mediator and outcome	11.7
Discussed mediation assumptions at all	42.2
Examined assumption of no interaction of exposure and mediator	2.5
Sensitivity analysis performed to mediation assumptions	1.5