Skip to main content
. 2022 Mar 7;24:64. doi: 10.1186/s13075-022-02730-z

Table 1.

Changes in cell clusters from the peripheral vasculature between WT and TNF-Tg mice by scRNAseq. The cluster numbers and cell types are aligned with those defined in Fig. 3. The cell numbers associated with each cluster are provided for both wild-type (WT) and tumor necrosis factor transgenic (TNF-Tg) groups along with the total cell counts for each cluster when these datasets are integrated together. To examine the changes in cell populations between the WT and TNF-Tg conditions, a percentage for each cell type was calculated by the number of cells in an individual cluster divided by the total cells within a single group (WT or TNF-Tg)

Cluster Cell Type WT # WT % TNF # TNF % Total #
1 LMCs 1433 26.11 552 16.28 1985
2 M2-Macrophages 1 1111 20.24 269 7.93 1380
3 VSMCs 751 13.68 580 17.10 1331
4 M1-Macrophages 522 9.51 331 9.76 853
5 Neutrophils 344 6.27 228 6.72 572
6 Inf Monocytes 66 1.20 494 14.57 560
7 Dendritic Cells 1 152 2.77 261 7.70 413
8 Dendritic Cells 2 306 5.58 24 0.71 330
9 Dying Cells 236 4.30 67 1.98 303
10 Pat Monocytes 7 0.13 192 5.66 199
11 Myeloid Progenitors 74 1.35 49 1.45 123
12 Mast Cells 98 1.79 17 0.50 115
13 Prolif Monocytes 70 1.28 45 1.33 115
14 T-Cells 1 45 0.82 64 1.89 109
15 Fibroblasts 75 1.37 30 0.88 105
16 RBCs 54 0.98 46 1.36 100
17 M2-Macrophages 2 80 1.46 14 0.41 94
18 Basophils 7 0.13 64 1.89 71
19 T-Cells 2 31 0.56 34 1.00 65
20 Endothelial Cells 26 0.47 30 0.88 56
Total 5488 100 3391 100 8879