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. 2022 Mar 7;12:27. doi: 10.1186/s13578-022-00762-1

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Potential competing endogenous RNA (ceRNA) regulatory network and protein–protein interactions (PPI) analysis in the pulmonary artery of HPH rats. A LncRNA/circRNA-miRNA-mRNA ceRNA regulatory network constructed in this study. The ceRNA regulatory network includes 10 miRNAs, 6 circRNAs, 7 lncRNAs, and 18 mRNAs. Red color indicates upregulated, green color indicates downregulated; circles indicate circRNAs, retangles indicate mRNAs, diamonds indicate lncRNAs, hexagons indicate miRNAs. B Co-expression analysis of DEmRNAs by STRING database. The squares represent gene association, more intense color of the squares represent higher association score. C Results of PPI analysis of DEmRNAs by STRING database. The balls represent the gene nodes, the connecting lines represent the interactions between genes and figures insides the balls represent protein structure