Table 2.
Univariate and multivariate Cox regression analysis for OS of HCC patients baseline
| Variables | Death group (N = 59) |
Alive group (N = 301) |
Univariate | Multivariate | ||
|---|---|---|---|---|---|---|
| P | HR(95% CI) | P | HR(95% CI) | |||
| GGT, U/L (≤60/>60) | 23(39.0%)/36(61.0%) | 181(60.1%)/120(39.9%) | 0.003 | 2.192(1.297-3.702) | – | – |
| DB, umol/l (≤8/>8) | 41(69.5%)/18(30.5%) | 256(85.0%)/45(15.0%) | 0.008 | 2.107(1.210-3.668) | – | – |
| AFP,ng/mL | ||||||
| ≤20 | 13(22.0%) | 154(51.2%) | – | – | – | |
| 20-400 | 15(25.5%) | 81(26.9%) | 0.037 | 2.204(1.048-4.633) | 0.077 | 1.977(0.928-4.21) |
| >400 | 31(52.5%) | 66(21.9%) | <0.001 | 3.991(2.088-7.629) | 0.001 | 3.093(1.589-6.023) |
| PNI | 45.50(26.6,65.8) | 49.40(26.50,73.30) | 0.001 | 0.940(0.906-0.974) | 0.014 | 0.953(0.917-0.99) |
| NLR | 1.93(0.52,73.33) | 2.06(0.40,25.75) | <0.001 | 1.072(1.037-1.107) | 0.001 | 1.061(1.026-1.098) |
| SIRI | 0.92(0.21,75.43) | 0.85(0.22,21.45) | <0.001 | 1.040(1.017-1.063) | – | – |
| MVI(yes/no) | 45(76.3%)/14(23.7%) | 135(44.9%)/166(55.1%) | <0.001 | 3.348(1.837-6.102) | 0.010 | 2.294(1.225-4.297) |
| Tumour diameter,cm | 6.39±3.33 | 4.71±2.95 | <0.001 | 1.129(1.064-1.198) | – | – |
| PVTT(yes/no) | 12(20.3%)/47(79.7%) | 18(6.0%)/283(94.0%) | <0.001 | 3.783(1.999-7.158) | 0.002 | 2.800(1.459-5.374) |