Figure 5:

Gene Ontology network analysis of processes enriched in the spectral library for each stage of asexual development. Gene Ontology (GO) terms significantly overrepresented in the transition between the 3 distinct stages of the asexual development (i, schizont- to ring-stage parasites; ii, ring- to trophozoite-stage parasites; iii, trophozoite- to schizont-stage parasites) were obtained using in-house methods and imported into REVIGO for network compilation. Visualization of network enrichment was performed using Cytoscape (v3.8.2). Each node is sized by increasing GO term uniqueness and coloured according whether the process is up (red) or down (blue) by comparison to the subsequent developmental stage. Grey bars connecting each node represent gene overlap between terms.