Table 1.
Phenotypic antimicrobial resistance and detected resistance genes.
| Isolate | phenotypic AMR | AMR genes | rpoB mutation |
|---|---|---|---|
| B1 | rifampicin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | His481Tyr |
| B2 | fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | none |
| B3 | rifampicin, fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Ser464Pro |
| B4 | rifampicin, fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Ser464Pro |
| B5 | fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Asp471Glu |
| B6 | fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Asp471Glu |
| B7 | fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Asp471Glu |
| B8 | fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Asp471Glu |
| B9 | fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Asp471Glu |
| D1 | fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Asp471Glu |
| D2 | fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Asp471Glu |
| D3 | oxacillin, fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Asp471Glu |
| D4 | fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Asp471Glu |
| D5 | oxacillin, fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Asp471Glu |
| D6 | fosfomycin | (AGly)apH, norA, lmrS, fosB, mepA, mepR, tet(38) | Asp471Glu |
(AGly)apH aminoglycoside resistance gene; norA multidrug resistance efflux pump gene norA; lmrS multidrug efflux pump lmrS; fosB; mepA and mepR multidrug efflux pump gene; tet(38) tetracyclin resistance gene; rpoB RNA polymerase beta subunit.