Table 2.

Summary of Informatics Implementations at Each Site

	Site
Informatics Task	Mass General Brigham	Dartmouth Hitchcock Health
Patient idenfication, establish eligibility
EHR		Identify eligible patients using existing codified result fields (i.e. BIRADS, LRADS, cervical cytology) Indicate eligible patients in EHR by adding mFOCUS-specific labels to patient record
Study Database	Query the EHR data warehouse daily to extract relevant reports (mammography, Pap smear, LDCT) Run reports through organ-specific natural language processing (NLP) to identify abnormal results Identify eligible patients using extracted data Indicate eligible patients in the EHR using a study-specific health maintenance reminder and automated problem list entry added to patient charts via web services
Intervention Delivery
EHR	Workbenches generated using mFOCUS-specific health maintenance reminder and automated problem list entries Send patient portal messages and generate letters via workbenches	Workbenches generated by searching for mFOCUS-specific labels in the patient record Send patient portal messages and generate letters via workbenches
Tracking Intervention Delivery
EHR		Record dates, outcomes of calls in workbenches Automated tracking of study outcomes (e.g. cancer diagnoses, completed follow-up tests)
Study Database	Record dates, outcomes of calls in sidecar Automated tracking of study outcomes (e.g. cancer diagnoses, completed follow-up tests)	Copy of the tracking information from EHR is pushed to sidecar for study monitoring