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. Author manuscript; available in PMC: 2022 Mar 7.
Published in final edited form as: Biosens Bioelectron. 2021 Nov 16;197:113808. doi: 10.1016/j.bios.2021.113808

Fig. 3.

Fig. 3.

Demonstration of the prolonged system showing ECG changes in response to different Amiodarone concentrations. (a) Representative ECG data obtained by the developed system and its change in ECG parameters due to different Amiodarone concentrations. (b) Bar chart describing the discrepancy of HR, QTc interval and QRS interval in ECG data with different Amiodarone concentrations (n = 8 fish). Quantification of heart rate decreased in response to Amiodarone (120.8 ± 5.3 BPM without treatment, 84.9 ± 9.1 BPM with 200 μM Amiodarone) while the QTc and QRS interval tend to increase (337.9 ± 7.5 msec with no drug and 44.2 ± 7.9 msec with 200 μM Amiodarone). *p < 0.05 (one-way analysis of variance with Turkey test). ns indicates not significant.