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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Biosens Bioelectron. 2021 Dec 3;199:113854. doi: 10.1016/j.bios.2021.113854

Fig. 1.

Fig. 1.

NanoVelcro Chips for enrichment and detection of both single CTCs and CTC clusters in NET patients’ blood. A) The majority of patients with advanced NETs have both CTCs and CTC clusters present in their peripheral blood. B) Cross-sectional view of NanoVelcro Chips. C) “Velcro-like” interactions between nanoscale cell-surface components (a.k.a., microvilli) and the anti-EpCAM-grafted SiNWS dramatically increase contact surface area, facilitating immunoaffinity-mediated capture of single NET CTCs and NET CTC clusters.