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. 2022 Feb 19;12(2):212–235. doi: 10.5498/wjp.v12.i2.212

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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

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Overview of laterodorsal tegmental nucleus efferent to reward-related brain areas and to thalamic centers involved in modulating cortical function. PFC: Prefrontal cortex; Thal: Thalamus; NAc: Nucleus accumbens; VTA: Ventral tegmental area; LDT: Laterodorsal tegmental nucleus.